Michael A. Kayser, DO, FACMG
I'm a clinical geneticist who helps people and systems make sense of complexity — especially when things don't behave the way we expect.
Medicine is where I started. Patterns are what I kept noticing. Careful thinking is what I'm trying to practice.
"I want to help — but I can't unsee the patterns once I see them."
That's the honest version. I didn't choose to become a pattern-watcher. But ignoring them started to feel less responsible than naming them carefully.
After years of working with families navigating complex genetic conditions, I started seeing something I couldn't un-see.
The patterns that matter in medicine — diagnostic uncertainty, cascading effects, the importance of timing — they show up everywhere else too. In how organizations make decisions. In how technology evolves. In how humans think about thinking.
Most systems behave well until they don't. And by the time they don't, it's often too late to ask why.
When systems can't pause, people get hurt. Most failures aren't from bad intent — they're from complexity outrunning care.
Three areas. They're more connected than they look.
Helping patients and families navigate complex biology with clarity and care. This is the work that taught me how to hold uncertainty without pretending it isn't there.
Observing how complex systems behave under pressure — and designing ways they can pause, adapt, and recover without causing harm. Not theory. Practice.
Working on how humans think with tools like AI — safely, responsibly, without pretending they're conscious or magical. Governance matters more than novelty.
I promise not to diagnose you with a pattern unless you ask.
I don't think I'm special. I think I'm attentive in a way that doesn't always fit job descriptions.
I started in medicine because I wanted to help people. I stayed because the patterns kept appearing — across families, across institutions, across the strange new landscape of technology and care.
This site exists because I needed somewhere to put all of it. Not to impress anyone. Just to make sense of it out loud.
If this resonates — whether you're a clinician, technologist, or just someone trying to make sense of complexity — we might have a useful conversation.